Postdoctoral Scientist Laboratory of Dr. Afrooz Rashnonejad, Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children’s Hospital
The primary focus of Rashnonejad lab is to develop AAV-based gene therapies for Charcot-Marie-Tooth type 1B (CMT1B) and Nemaline Myopathy. Our lab is in the Center for Gene Therapy at Nationwide Children’s Hospital (NCH). The NCH Center for Gene Therapy has a long track record of training leaders in gene therapy and has been the site of the development of the first FDA-approved AAV-mediated gene therapy for neuromuscular disease (SMA), and several other gene therapies have reached clinical trials.
Location: Columbus, Ohio, USA
Salary: Based on NIH Post-doctoral stipend guidelines, benefits include family health insurance, matched retirement account
Discipline: Life Sciences, Gene Therapy, Cellular and Molecular Biology, RNAi, CRISPR, Neurological diseases, Peripheral Neuropathy, neuromuscular diseases, Adeno-Associated Viral (AAV) vectors, Immunology,
Qualifications Required:
- PhD, MD/PhD, or MD (or equivalent degrees) in Cellular and Molecular biology, Biomedicine, Biotechnology, Biochemistry, Neuroscience, Genetics, Immunology, or related disciplines who are interested in developing gene therapies for neurodegenerative and muscular disorders
- Creative, highly motivated, and ambitious candidates
- Ability to lead independent research projects and design experiments
- Prior experience and background in gene therapy research are preferred but not required; we are interested in developing new investigators into the field
- Extensive experience in molecular biology (cloning, western blot, qRT-PCR, and fluorescent staining)
- Prior experience with tissue cryosectioning and histological assays, mouse colony maintenance, mouse surgery and injections is
- Ability to do technical writing, and good communication skills.
- US citizenship or permanent residency is not required.
The Post-Doctoral Scientist will participate in focused research investigations on these topics:
- Viral Gene Therapy
- Cell-Specific Gene Expression
- Charcot-Marie-Tooth Disease
- Nemaline Myopathy
We can offer potential candidates:
- Up to 5 years of salary and project support
- Substantial financial support to develop new ideas
- Strong mentorship to support career development toward academia or industry jobs
State-of-the-art laboratories and core facilities - Affiliation with The Ohio State University College of Medicine
- Collaborations with clinical experts in neuromuscular and neurological diseases
On-site GMP AAV vector manufacturing
Postdoctoral Scientist , Postdoctoral Scientist
