Latest PhD Biochemistry Job. Fresher opening Scientist position. Apply online by checking the details attached below. Aequor Information Technologies job opening.
Job role – Scientist I
Location: Framingham, MA, United States
Job Description
- Function as a coordinator to manage external testing at contract laboratories.
- Lead several analytical studies simultaneously to qualify single use components used during manufacturing of biologics.
- Author protocols and reports.
- Coordinate sample shipment to contract laboratories.
- Follow company shipping procedures and compliances.
- Lead investigations to resolve non-conformance results and to identify root causes. Will be required to analyse samples to identify compounds, develop and validate quantitation method on ICP-MS/OES, LC-MS and GC-MS.
- Familiarity with NIST and Wiley libraries is a plus.
- Meet project/customer requirements and timelines.
Basic Qualifications for Latest PhD Biochemistry Job:
- Work experience in an analytical laboratory. Ph.D. in Chemistry, Biochemistry, and Analytical chemistry with research experience involving multiple analytical techniques.
- Good communication skills (verbal and written), math skills, and general computer skills.
- Experience writing and revising documents (e.g. testing methods, protocols, reports).
- Experience utilizing Microsoft Word, Excel, and Outlook (MS 2010). Experience participating in teams and collaborative work environments..
- Years of Experience: 0 – 3 Years
- Manager is Open to Full Scope of experience, Must have Ph.D. Entry + Level Experience 0 -3 Years
- Required Degree in related Protein Sciences
- Open to candidates willing to relocate at their own expense
- Free Parking/ However limited public transportation to this site
Must have skills:
• PHD Degree
• 0-3 Years of Experience
• Experience working with proteins
• Expected to present results, strong presentation skills
• Additional research/ writing skills required
• Experience with SOME of the following techniques:
o Analytical Ultracentrifugation (AUC)
o Dynamic light scattering (DLS)
o Differential scanning calorimetry (DSC)
o Circular dichroism (CD)
o Size exclusion chromatography (SEC)
o Ion exchange chromatography (IEC, WCX, WAX)
o Hydrophobic interaction chromatography (HIC)
o Electrospray mass spec (Client-MS, LC-MS)
o Capillary electrophoresis (CE-SDS, SDS-PAGE)
o Capillary isoelectric focusing (cIEF)
Preferred skills:
• Experience measuring biophysical properties of proteins with any chromatography
• Demonstrated method development leadership
• Evidenced participation or leadership in structural biology or biophysical characterization research
Hello, everyone! We are here to offer you a set of interview questions and answers to help you prepare effectively for your upcoming interview for the Latest PhD Biochemistry Job. We hope these resources will assist you in performing well during your interview.”
Can you describe your experience with managing external testing at contract laboratories and coordinating sample shipments?
Sample Answer: In my previous role, I played a key role in managing external testing at contract laboratories. This involved liaising with the labs to ensure they had all the necessary information, samples, and protocols. I also coordinated sample shipments, adhering to our company’s shipping procedures and ensuring compliance with all relevant regulations. These experiences have prepared me well for the responsibilities outlined in this job description.
Could you provide an example of a challenging analytical study you led involving the qualification of single-use components for biologics manufacturing?
Sample Answer: In a previous position, I led an analytical study to qualify single-use components for biologics manufacturing. One of the challenges we faced was ensuring the compatibility of these components with our manufacturing processes. We conducted a comprehensive study that involved multiple analytical techniques, including LC-MS and GC-MS, to identify potential issues. Through careful analysis and collaboration with the team, we were able to develop and validate quantitation methods, ultimately ensuring the quality of our manufacturing process.
How do you approach root cause analysis when dealing with non-conformance results in analytical testing?
Sample Answer: When faced with non-conformance results, my approach is systematic. I begin by conducting a thorough investigation to identify the root causes. This often involves analyzing samples using techniques like ICP-MS/OES, LC-MS, and GC-MS to pinpoint any anomalies. I also collaborate closely with colleagues to gather insights and conduct a comprehensive review of the process. Once the root causes are identified, I work on implementing corrective actions to prevent recurrence.
Can you elaborate on your experience with analytical techniques such as Analytical Ultracentrifugation (AUC), Dynamic Light Scattering (DLS), and Differential Scanning Calorimetry (DSC)?
Sample Answer: I have experience with a range of analytical techniques, including AUC, DLS, and DSC. These techniques are essential for characterizing the biophysical properties of proteins. For example, AUC is valuable for studying protein interactions and sedimentation behavior, while DLS helps in determining particle size and stability. DSC is crucial for understanding protein stability and thermal unfolding. I have successfully utilized these techniques in my previous roles to advance biopharmaceutical research.
How do you stay updated with the latest advancements in analytical chemistry and protein sciences?
Sample Answer: Staying updated in my field is a priority for me. I regularly read scientific journals, attend conferences, and participate in webinars related to analytical chemistry and protein sciences. Additionally, I engage in discussions with colleagues and experts in the field to exchange knowledge and stay informed about emerging techniques and technologies. This commitment to continuous learning ensures that I can apply the latest advancements to my work effectively.
Can you provide an example of a situation where you demonstrated leadership in method development for biophysical characterization?
Sample Answer: In my previous role, I led a method development project aimed at improving the biophysical characterization of proteins. We were working on a challenging project, and existing methods were not yielding the desired results. I took the initiative to assemble a cross-functional team, consisting of scientists with expertise in various techniques. Together, we evaluated and optimized existing methods, and in some cases, developed entirely new protocols. This collaborative effort resulted in more accurate and robust methods for biophysical characterization, demonstrating my leadership in this area.
