Laboratory Research Scientist at Francis Crick Institute in London! Apply Now!
Laboratory Research Scientist
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Locations: London
Time Type: Full time
Posted On: Posted 5 Days Ago
Job Requisition ID: R1831
Salary for this Role: From £31,675 per annum plus benefits, subject to skills and experience
Job Title: Laboratory Research Scientist
Reports to: Pontus Skoglund
Closing Date: 03/Oct/2024 23.59 GMT
Job Description:
Job title: Laboratory Research Scientist
Reporting to: Dr Pontus Skoglund (Group Leader)
Contract term: This is a full-time, fixed-term (2 year) position on Crick terms and conditions of employment.
Summary
A position as a Laboratory Research Scientist (LRS) has been created at the Ancient Genomics Lab (www.skoglundlab.org) of the Francis Crick Institute, led by Dr Pontus Skoglund and working directly under Mrs Monica Kelly.
The post holder will be involved in the operation of the specialised ancient DNA clean room facility; Post PCR and skeletal sample processing. Applications are welcome from candidates with excellent organisational skills, a track record of high-fidelity laboratory work, and expertise in molecular biology techniques and preferably some bioarchaeology experience.
The Role
The role of a Laboratory Research Scientist in the Crick is diverse and rewarding. The role covers a wide range of different functions and allows for continuity of lab operations. The role offers support to one or more scientific projects or programmes. Typical activities include:
Collaborating with other lab members on/Assisting other lab members with/ research projects.
Providing experimental or technical support to other lab members.
Providing technical expertise/ input for the development, refinement and troubleshooting of relevant methodologies.
Participating in academic activities, including group meetings and journal clubs, seminars, and scientific meetings.
Organisation and management of the laboratory, including maintaining laboratory databases, ordering of laboratory supplies, monitoring budgets, and routine maintenance of laboratory equipment.
Training and supervising other lab members in key techniques and protocols, lab operations, and equipment use.
Liaising with Science Operations and attending key quadrant meetings.
Writing risk assessments and SOPs and providing safety guidance to lab members.
The Research Group
Dr Skoglund’s laboratory focuses on developing molecular and computational tools to retrieve ancient genomes from past populations in conjunction with statistical population genetic approaches, with the overarching goal to study how ecological and cultural factors have shaped human population structure and biology during momentous transitions in prehistory.
Details of research projects currently being undertaken can be seen at: https://www.crick.ac.uk/research/labs/pontus-skoglund
Key Responsibilities
These include but are not limited to:
Ancient DNA retrieval.
Bone and tooth powder extraction from skeletal material, genomic library preparation and targeted capture of genomic DNA.
Automation. Execution of ancient DNA workflows on Agilent Bravo Workstations.
Pooling and fragment restriction, prior to whole-genome shotgun sequencing.
Genome sequencing. Organize and enable sequencing by liaising with the Advanced Sequencing Technology Platform core facility at the Crick.
Ethical handling of human remains (British Association for Biological Anthropology and Osteoarchaeology guidelines).
Skeletal sample handling, shipping and cataloguing.
Manual first molecular digestion step.
Targeted hybridisation enrichment for human and canine SNP targets and pathogens.
Scientific interaction and publication. Participation in scientific meetings within the group and wider community. Contribute to publications and presentations.
Experience and Competencies
The post holder should embody and demonstrate our core Crick values: Bold; Open; Collegial
Essential Qualifications, Experience and Competencies:
BSc in Biology, Biochemistry or a related field, or equivalent experience
Experience with molecular biology laboratory work
Strong skills in organising and recording experiments
Strong collaborative ability and teamwork experience
Ability to prioritise and manage own time
Ability to communicate and present data
Desirable
Experience with next-generation sequencing and genomics
Experience with automated liquid handling instruments (Agilent and/or Hamilton)
Experience with the use of databases
Strong skills in organising and recording sample handling
Beneficial
Experience with bioinformatics processing of genomic sequence data
Experience with ancient DNA extraction from skeletal material
Experience in DNA library preparation methods and high-throughput sequencing
Experience with managing ancient skeletal material
Keywords: Laboratory Research Scientist, Science, Molecular Biology, Bioarchaeology, London, Job, Francis Crick Institute. Laboratory Research Scientist at Francis Crick Institute in London! Apply Now!
