Entrada Therapeutics Hiring Biochemistry We are a tight-knit team of experts and leaders in both therapeutics development and rare diseases, and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.
The Perfect Addition to Our TeamYou are a highly motivated, collaborative, communicative and enthusiastic scientist excited to support the company at a critical stage in its growth trajectory in developing oligonucleotide therapeutics. You support our team of drug discovery scientists as we perform analytical assays and biophysical characterization of Non-Viral delivery based nanotherapeutic formulations. Your ability and desire to thrive in a nimble, fast-paced, results-driven environment will set you up for success.The OpportunityIn this fast-paced interdisciplinary role you will be working with various team of senior scientists conducting analytical assays, biophysical characterization and supporting non-viral nanoparticle formulations. You will have the opportunity to contribute to synthesis, purification, and characterization of oligonucleotide constructs for SAR studies. You’ll be expected to master techniques like RNA quantification, DLS, HPLC, MALDI-TOF, LC-MS as well as lipid and peptide bioconjugations.The Necessities
At Entrada, our passion for science, our devotion to patients and our values drive our behavior:
Humanity: We genuinely care about patients and about one another
Tenacity: We are relentless and persistent in the pursuit of developing therapies for patients
Creativity: We are creative problem solvers
Collaboration: We are more than the sum of our parts
Curiosity: We have a growth mindset and push conventional thought and theory
Job Title: Research Associate II, Discovery Chemistry
Location Boston, MA
Eligbility Criteria:
- BS/MS in biochemistry, molecular biology, pharmaceutical sciences, analytical chemistry, chemical biology, medicinal chemistry, or other relevant scientific discipline
- Familiarity with plate-based fluorescence assays and/or nucleic acid based bioanalytical assays is required.
- Hands on experience with analytical characterization and quantification of RNA (RiboGreen assay, Nanodrop, DLS & Zeta measurements) is highly desirable.
- Experience with peptide, lipid and nucleic acid bioconjugations is highly desirable.
- Experience with Lipid Nanoparticle Formulations is highly desirable.
- Experience with high throughput screening assays is a plus
- Experience with bioconjugations, reverse-phase and ion-exchange based purification and LC-MS / MALDI-TOF characterization is a plus.
A strong goal-oriented team player mindset with excellent communication (written and verbal) and interpersonal skills, an attention to detail and a demonstrated ability to work independently with guided supervision, while maintaining the highest ethical and scientific standards.
The Perks
As a team member here at Entrada, you’ll have access to competitive health, dental and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance. You’ll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.
Entrada Therapeutics Hiring Biochemistry
